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Comparison of three commercial molecular assays for detection of rifampin and isoniazid resistance among Mycobacterium tuberculosis isolates in a high-HIV-prevalence setting

机译：三种商业分子检测方法用于检测高HIV感染率的结核分枝杆菌菌株中利福平和异烟肼耐药性的比较

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In a head to head comparison of the MTBDRplus Version 2.0 (Hain Lifescience), Xpert®MTB/RIF (Cepheid) and the Anyplex™ MTB/NTM (Seegene) assays we demonstrate equalsensitivity (59/61; 96.7%) and specificity (53/54; 98.1%) for detecting rifampicin resistancewith further analysis of discordances. The Xpert does not detect Isoniazid resistance whileAnyplex showed high false positivity.

机译：在对MTBDRplus 2.0版（Hain Lifescience），Xpert®MTB/ RIF（造父变星）和Anyplex™MTB / NTM（Seegene）测定法进行的正面对比中，我们证明了同等敏感性（59/61; 96.7％）和特异性（53） / 54; 98.1％）用于检测利福平耐药性并进一步分析不一致之处。 Xpert未检测到异烟肼抗性，而Anyplex显示出较高的假阳性。

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Onwuegbuna, O.; Strydom, Kathy-Anne; Ismail, Farzanah; Matabane, M.M.Z.; Omar, S.V. (Shaheed Vally); Ismail, Nabila;
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1. Comparison of Three Commercial Molecular Assays for Detection of Rifampin and Isoniazid Resistance among Mycobacterium tuberculosis Isolates in a High-HIV-Prevalence Setting [J] . K. Strydom, F. Ismail, M. M. Z. Matabane, Journal of Clinical Microbiology . 2015,第9期

机译：在HIV高流行背景下检测结核分枝杆菌菌株对利福平和异烟肼耐药性的三种商业分子检测方法的比较
2. Validation of the FluoroType MTBDR Assay for Detection of Rifampin and Isoniazid Resistance in Mycobacterium tuberculosis Complex Isolates [J] . Doris Hillemann, Carsten Haasis, S?nke Andres, Journal of Clinical Microbiology . 2018,第6期

机译：用于检测结核分枝杆菌复杂分离物中的利福平和异烟肼耐药性的Fluorotype MTBDR检测方法的验证
3. Evaluation of the Genotype MTBDR Assay for Rapid Detection of Rifampin and Isoniazid Resistance in Mycobacterium tuberculosis Isolates [J] . Cengiz Cavusoglu, Ajda Turhan, Pinar Akinci, Journal of Clinical Microbiology . 2006,第7期

机译：快速检测结核分枝杆菌菌株中利福平和异烟肼抗性的基因型MTBDR分析方法的评估
4. Molecular Genetic Analysis of Nucleotide Polymorphisms Associated with Rifampin and Isoniazid Resistance in Human Isolates of Mycobacterium tuberculosis [C] . Dorina Banica, Emilia Cazacu, Dan Otelea, International Symposium on Communications, Control and Signal Processing . 2008

机译：分枝杆菌结核病人分离株核苷酸多态性核苷酸多态性的分子遗传分析
5. Results of a randomized, controlled trial to assess the toxicity and patient adherence with two short-course regimens for the prevention of tuberculosis, a two-month regimen of rifampin and pyrazinamide or a four-month regimen of rifampin only, in comparison with a control regimen of six-months-isoniazid. [D] . Geiter, Lawrence James. 1997

机译：与对照相比，采用两种短期疗程预防结核病，两个月利福平和吡嗪酰胺治疗或仅四个月利福平治疗，评估毒性和患者依从性的随机对照试验结果六个月异烟肼的治疗方案。
6. Comparison of Three Commercial Molecular Assays for Detection of Rifampin and Isoniazid Resistance among Mycobacterium tuberculosis Isolates in a High-HIV-Prevalence Setting [O] . K. Strydom, F. Ismail, M. M. Z. Matabane, 2015

机译：在HIV高流行背景下检测结核分枝杆菌菌株对利福平和异烟肼耐药性的三种商业分子检测方法的比较
7. Evaluation of the Genotype MTBDR Assay for Rapid Detection of Rifampin and Isoniazid Resistance in Mycobacterium tuberculosis Isolates [O] . Cavusoglu, Cengiz, Turhan, Ajda, Akinci, Pinar, 2006

机译：快速检测结核分枝杆菌菌株中利福平和异烟肼抗性的基因型MTBDR分析方法的评估

Comparison of three commercial molecular assays for detection of rifampin and isoniazid resistance among Mycobacterium tuberculosis isolates in a high-HIV-prevalence setting

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